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1 Introduction Fracture healing is a remarkably orchestrated biological process that recapitulates aspects of embryonic skeletal development, requiring the precise spatiotemporal coordination of inflammation, angiogenesis, osteogenesis, and remodeling ( The pathophysiology of compromised bone healing is multifactorial, encompassing mechanical instability, inadequate vascularization, impaired osteogenic cell function, persistent inflammation, and infection ( Ferroptosis, first characterized by Dixon et al

10.1039/p29950000259 24 Hermida-AmeijeirasA.Mndez-AlvarezE.Snchez-IglesiasS.Sanmartn-SurezC.Soto-OteroR

Physiol Res 72:403414

8 weeks (1 vial): 3 mL 1 10 mL bottle 12 weeks (2 vials): 6 mL 1 10 mL bottle Alcohol Swabs: One for the vial stopper + one for the injection site each day

PMC10056213 Subcutaneous injection osmolality, pH, and volume effects on pain and absorption

Carere RG